Research
I have been involved in multiple clinical research studies in the pathophysiology of type 2 diabetes. My main focus has been dissecting the underlying mechanisms of insulin resistance and beta cell dysfunction, particularly how elevated free fatty acids induce insulin resistance and the natural history of development of type 2 diabetes as well as pharmacological interventions to prevent type 2 diabetes. I am currently involved in the validation and mechanism of action of many of the more recent medications used to treat and prevent Type 2 diabetes. My other field of interest is metabolic effects of sex hormones, particularly long-term effects of testosterone and estrogen.
Relevant Diseases
Diabetes, Insulin resistance, impaired glucose tolerance, hypogonadism, transgender medicine
Techniques
Insulin clamps, glucose tolerance test
Diabetes/Pathogenesis and Mechanism of Action of Newer Anti-diabetic Agents
I have been involved in multiple clinical research studies in pathophysiology of type 2 diabetes. My main focus has been dissecting the underlying mechanisms of insulin resistance and beta cell dysfunction, particularly how elevated free fatty acids induce insulin resistance and the natural history of development of type 2 diabetes as well as pharmacological interventions to prevent type 2 diabetes. I am currently involved in the validation and mechanism of action of many of the more recent medications used to treat and prevent Type 2 diabetes. My other field of interest is metabolic effects of sex hormones, particularly long-term effects of testosterone and estrogen.
Related Diseases: Diabetes, Insulin resistance, impaired glucose tolerance, hypogonadism, transgender medicine
Techniques: Insulin clamps and glucose tolerance